Summary: (from NCBI-Entrez) ..[read more]This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in thi
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site (Grieshammer et al. 2004).Syndecan is a necessary component of Slit/Robo signaling and is required in the Slit target cells (Steigemann et al. 2004).
Receptor ROBO2 interacts with:
All interactions in Receptor family ( Roundabout )
Gene Expression data