Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also
Expression and dynamic modulation of the human granulocyte colony-stimulating factor receptor (CD114) in immature and differentiated myeloid cells (Jilma et al. 2000).Mutational analysis of the G-CSFR indicated that the N-terminal region of its cytoplasmic domain is sufficient to transduce the proliferation signal into cells, while the C-terminal region plays an essential role in transducing the differentiation signal.
(Fukunaga et al. 1993)
CSF3R - COLONY STIMULATING FACTOR 3 RECEPTOR ISOFORM A PRECURSOR
Family:Cytokine1R|OSMR
Receptor CSF3R interacts with:
All interactions in Receptor family ( Cytokine1R|OSMR )
Gene Expression data