Summary: (from NCBI-Entrez)
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The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell traff
Receptor CCR4 interacts with:
Ligand CCL17 - CHEMOKINE (C-C MOTIF) LIGAND 17[read more..] The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4.
J Biol Chem. 1997 Ligand CCL22 - CHEMOKINE (C-C MOTIF) LIGAND 22[read more..] Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.
J Biol Chem. 1998 Ligand CCL2 - SMALL INDUCIBLE CYTOKINE A2[read more..] Migration of cytotoxic T lymphocytes toward melanoma cells in three-dimensional organotypic culture is dependent on CCL2 and CCR4.
Eur J Immunol. 2006
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OocyteDevelopment
PreEmbryoHuman
PreEmbryoMouse
PreimplantMmEmbryo
Follicle_Maturation_and_Ovulation_POnly
Castrillon_Ovary_Set
Castrillon_Soma_Set
EmbryonicOvary
Mm_Testis_Development
NormEndometrium
PituitaryAdenoma
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Preimplantation Mouse Embryo
Description :
Fields :
Experiment: Testis development
Testes of mice at days 0, 3, 6, 8, 10, 14, 18, 20, 30, 35, and 56 of age.
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{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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Experiment: Pituitary adenoma subtypes
Normal pituitary, pituitary adenomas secreting GH, PRL, or ACTH, and non-functioning adenoma.
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{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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Experiment: Preimplantation mouse embryo
{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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Receptor CCR4 interacts with:
All interactions in Receptor family ( 7TM|A|Polypeptide|Chemokine/interleukin )
Gene Expression data