Summary: (from NCBI-Entrez) ..[read more]Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17
Yao Z, et al. (Cytokine. 1997)characterized the human interleukin (IL)-17 receptor.They found that mnoclonal antibodies (mAbs) generated against the hIL-17R were able to block the IL-17-induced production of cytokine from human foreskin fibroblast (HFF) cells. Binding studies suggest that recombinant hIL-17 binds to the hIL-17R with low affinity.
All interactions in Receptor family ( IL-17 Receptors )
Gene Expression data