Summary: (from NCBI-Entrez) ..[read more]Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor a
The adrenergic receptors mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine, the latter is converted upon dopamine beta-hydroxylase.