Summary: (from NCBI-Entrez) ..[read more]Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the
Baloh et al. (1997) reported that TrnR2 is a novel receptor that mediates neurturin and GDNF signaling through Ret. Klein et al. (1997) also found A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.