NGFRAP1 - NERVE GROWTH FACTOR RECEPTOR (TNFRSF16) ASSOCIATED PROTEIN 1 ISOFORM A
Family: Other
Synonyms: NGFR-ASSOCIATED PROTEIN 1|p75(NTR)-ASSOCIATED CELL DEATH EXECUTOR, NADE
External
links: Entrez Gene ,
Omim
Receptor NGFRAP1 interacts with:
Receptor NTRK2 - NEUROTROPHIC TYROSINE KINASE, RECEPTOR, TY ... and Ligand BDNF - BRAIN-DERIVED NEUROTROPHIC FACTOR[read more..] Levine ES,et al. (PNAS,1995) demonstrated that brain-derived neurotrophic factor (BDNF) signals via the tyrosine kinase receptor (Ntrk2/TrkB).
Receptor NTRK2 - NEUROTROPHIC TYROSINE KINASE, RECEPTOR, TY ... and Ligand NTF5 - NEUROTROPHIN 5[read more..] Ip NY et al. (Neuron. 1993) discussed all of the Trks display similar dose responses to their "preferred" ligands in neuronal as compared with nonneuronal cells (i.e., NGF for TrkA, BDNF and NT-4/5 for TrkB, and NT-3 for TrkC), providing evidence against a role for accessory molecules expressed in neurons in generating receptors that would allow for responses to lower concentrations of the neurotrophins. However, we find that a neuronal environment does restrict the Trks in their ability to respond to their "nonpreferred" neurotrophin ligands.
Receptor NGFR - TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY ...[read more..]
All interactions in Receptor family ( Other )
Gene Expression data
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OocyteDevelopment
PreEmbryoHuman
PreEmbryoMouse
PreimplantMmEmbryo
Follicle_Maturation_and_Ovulation_POnly
Castrillon_Ovary_Set
Castrillon_Soma_Set
EmbryonicOvary
Mm_Testis_Development
NormEndometrium
PituitaryAdenoma
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Preimplantation Mouse Embryo
Description :
Fields :
Experiment: Testis development
Testes of mice at days 0, 3, 6, 8, 10, 14, 18, 20, 30, 35, and 56 of age.
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Experiment: Pituitary adenoma subtypes
Normal pituitary, pituitary adenomas secreting GH, PRL, or ACTH, and non-functioning adenoma.
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Experiment: Preimplantation mouse embryo
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