Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleu
The receptor for interleukin (IL)-7 (IL-7R) includes a unique alpha chain as well as a common gamma chain shared with the receptors for IL-2 and IL-4. Engagement of the IL-7R activates the intracellular enzyme phosphatidylinositol (PtdIns) 3-kinase (Venkitaraman & Cowling 1994).
Kondo M, et al.(Science, 1994) found that the IL-2 receptor gamma chain participates in the functional high-affinity receptor complexes for IL-7 that are involved in the differentiation of T and B cells.
IL7R - INTERLEUKIN 7 RECEPTOR
Family:Cytokine1R
Receptor IL7R interacts with:
All interactions in Receptor family ( Cytokine1R )
Gene Expression data