Summary: (from NCBI-Entrez) ..[read more]The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha
Form and function: the laminin family of heterotrimers. Laminin-1 is composed of the three subunits alpha-1, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-1 is composed of the three subunits alpha-1, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-2 is composed of the three subunits alpha-2, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-2 is composed of the three subunits alpha-2, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-5 is composed of the three subunits alpha-3A, beta-3 and gamma-2 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-5 is composed of the three subunits alpha-3A, beta-3 and gamma-2 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-8 is composed of the three subunits alpha-4, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-10 is composed of the three subunits alpha-5, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-11 is composed of the three subunits alpha-5, beta-2 and gamma-1 (Colognato & Yurchenco 2000).
Receptor ITGB1 - INTEGRIN BETA-1 PRECURSORandLigand ADAM9 - A DISINTEGRIN AND METALLOPROTEINASE DOMAIN ...[read more..]
Nath et al. (2000) reported that meltrin gamma (ADAM-9)can function as a cell adhesion molecule via its disintegrin domain. They demonstrated that a murine meltrin gamma-Fc (Mel gamma -Fc) fusion protein binds to the integrin alpha-6-beta-1 on the surface of fibroblast cell lines.
Receptor ITGB1 - INTEGRIN BETA-1 PRECURSORandLigand ADAM2 - A DISINTEGRIN AND METALLOPROTEINASE DOMAIN ...[read more..]
Chen & Sampson (1999) concluded that fertilin-beta binds directly to the alpha-6-beta-1 integrin on the egg surface and this partnership mediates sperm-egg fusion.
Receptor ITGA6 interacts with:
All interactions in Receptor family ( Integrins|ITAB )
Gene Expression data