Summary: (from NCBI-Entrez) ..[read more]ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join wit
Identification of a novel binding site to the integrin alpha-2b-beta-3 located in the C-terminal heparin-binding domain of human plasma fibronectin (Mohr et al. 19960.
ICAM-4 is a red cell intercellular adhesion molecule. Cell transfectants expressing various integrins were used to demonstrate that integrins alpha-L-beta-2, alpha-M-beta-2, and alpha-IIb-beta-3 bind specifically and dose dependently to the recombinant ICAM-4-Fc protein. Cell surface ICAM-4 interacts with the cell surface alpha-V-beta-3 integrin (Hermand et al. 2004).
ITGA2B - INTEGRIN ALPHA-IIB PRECURSOR
Family:Integrins
Receptor ITGA2B interacts with:
All interactions in Receptor family ( Integrins )
Gene Expression data