Zhang et al. (1998) found that the recombinant MDC-15 disintegrin-like domain of ADAM-15 specifically interacts with alpha-v-beta-3 but not with the other integrins. These finding were supported also by (Nath et al. 1999)

Zhang et al. (1998) found that the recombinant MDC-15 disintegrin-like domain of ADAM-15 specifically interacts with alpha-v-beta-3 but not with the other integrins. These finding were supported also by (Nath et al. 1999).

Recombinant ADAM 23 promotes attachment of different human cells of neural origin, such as neuroblastoma cells. Analysis of ADAM 23 binding to integrins revealed a specific interaction with alphavbeta3, mediated by a short amino acid sequence present in its putative disintegrin loop (Cal et al. 2000).

Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3. J Biol Chem. 1998 .

Identification of a novel binding site to the integrin alpha-2b-beta-3 located in the C-terminal heparin-binding domain of human plasma fibronectin (Mohr et al. 19960.

Distinct ligand-binding modes for integrin alpha-5-beta-3-mediated adhesion to fibronectin versus vitronectin (Boettiger et al. 2001).

Integrin alpha(v)beta(3)/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells (Hapke et al. 2001).

ICAM-4 is a red cell intercellular adhesion molecule. Cell transfectants expressing various integrins were used to demonstrate that integrins alpha-L-beta-2, alpha-M-beta-2, and alpha-IIb-beta-3 bind specifically and dose dependently to the recombinant ICAM-4-Fc protein. Cell surface ICAM-4 interacts with the cell surface alpha-V-beta-3 integrin (Hermand et al. 2004).

ICAM-4 is a red cell intercellular adhesion molecule. Cell transfectants expressing various integrins were used to demonstrate that integrins alpha-L-beta-2, alpha-M-beta-2, and alpha-IIb-beta-3 bind specifically and dose dependently to the recombinant ICAM-4-Fc protein. Cell surface ICAM-4 interacts with the cell surface alpha-V-beta-3 integrin (Hermand et al. 2004).