ADCYAP1R1 - TYPE I ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR PRECURSOR Family:7TM|B|Polypeptide
Synonyms:PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE RECEPTOR, TYPE I|PACAP RECEPTOR, TYPE I ADCYAP1R1
External
links:Entrez Gene, Omim
Summary: (from NCBI-Entrez) ..[read more]This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of
Structural motifs of pituitary adenylate cyclase-activating polypeptide (PACAP) defining PAC1-receptor selectivity.
Pituitary adenylate cyclase-activating polypeptide (PACAP) interacts with three types of PACAP/VIP-receptors. The PAC1-receptor accepts PACAP as a high affinity ligand but not vasoactive intestinal peptide (VIP) similarly binding to VPAC1- and VPAC2-receptors.
REGULATORY PEPTIDES 1999 .
Alternative splicing in the N-terminal extracellular domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor modulates receptor selectivity and relative potencies of PACAP-27 and PACAP-38 in phospholipase C activation.
J Biol Chem. 1996 .
Alternative splicing in the N-terminal extracellular domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor modulates receptor selectivity and relative potencies of PACAP-27 and PACAP-38 in phospholipase C activation.
J Biol Chem. 1996 .
ADCYAP1R1 - TYPE I ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR PRECURSOR
Family:7TM|B|Polypeptide
Receptor ADCYAP1R1 interacts with:
All interactions in Receptor family ( 7TM|B|Polypeptide )
Gene Expression data