Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosph
AVP receptors are classified into at least 3 subtypes: V1a, V1b, and V2. The V1a receptor (600821) has been localized in the liver, vascular smooth muscle, brain, mesangial cells, and platelets. The V2 receptor (304800) is exclusively expressed in the kidney, and defects in this receptor result in nephrogenic diabetes insipidus. Sugimoto et al. (1994) cloned the V1b receptor from a cDNA library of human pituitary. (The gene is also referred to as AVPR3.)
Receptor AVPR1A interacts with:
All interactions in Receptor family ( 7TM|A|Polypeptide|Vasopressin/oxytocin )
Gene Expression data