Summary: (from NCBI-Entrez)
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The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP
Receptor CCR3 interacts with:
Ligand CCL5 - CHEMOKINE (C-C MOTIF) LIGAND 5[read more..] Cloning, expression, and characterization of the human eosinophil eotaxin receptor.
J Exp Med. 1996 Ligand CCL7 - CHEMOKINE (C-C MOTIF) LIGAND 7[read more..] Cloning, expression, and characterization of the human eosinophil eotaxin receptor.
J Exp Med. 1996 Ligand CCL8 - CHEMOKINE (C-C MOTIF) LIGAND 8[read more..] Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.
J Clin Invest. 1997 Ligand CCL11 - CHEMOKINE (C-C MOTIF) LIGAND 11[read more..] Cloning, expression, and characterization of the human eosinophil eotaxin receptor.
J Exp Med. 1996 Ligand CCL13 - CHEMOKINE (C-C MOTIF) LIGAND 13[read more..] Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.
J Clin Invest. 1997 Ligand CCL15 - CHEMOKINE (C-C MOTIF) LIGAND 15[read more..] Characterisation of macrophage inflammatory protein-5/human CC cytokine-2, a member of the macrophage-inflammatory-protein family of chemokines.
Eur J Biochem. 1997 Ligand CCL24 - CHEMOKINE (C-C MOTIF) LIGAND 24[read more..] Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.
J Biol Chem. 1999 Ligand CCL26 - CHEMOKINE (C-C MOTIF) LIGAND 26[read more..] Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.
J Biol Chem. 1999 Ligand CCL28 - CHEMOKINE (C-C MOTIF) LIGAND 28[read more..]
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OocyteDevelopment
PreEmbryoHuman
PreEmbryoMouse
PreimplantMmEmbryo
Follicle_Maturation_and_Ovulation_POnly
Castrillon_Ovary_Set
Castrillon_Soma_Set
EmbryonicOvary
Mm_Testis_Development
NormEndometrium
PituitaryAdenoma
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Preimplantation Mouse Embryo
Description :
Fields :
Experiment: Testis development
Testes of mice at days 0, 3, 6, 8, 10, 14, 18, 20, 30, 35, and 56 of age.
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Experiment: Pituitary adenoma subtypes
Normal pituitary, pituitary adenomas secreting GH, PRL, or ACTH, and non-functioning adenoma.
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Experiment: Preimplantation mouse embryo
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Receptor CCR3 interacts with:
All interactions in Receptor family ( 7TM|A|Polypeptide|Chemokine/interleukin )
Gene Expression data