Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related pep
Liaw CW, et al. (Endocrinology. 1996 ) cloned two CRH receptors and the CRF- and sauvagine-induced accumulation of intracellular cAMP could be competitively inhibited by the CRF receptor antagonist D-Phe-CRF.
Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor.
Nat Med. 2001
Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor.Proc Natl Acad Sci U S A. 2001
Receptor CRHR2 interacts with:
All interactions in Receptor family ( 7TM|B|Polypeptide )
Gene Expression data