Summary: (from NCBI-Entrez) ..[read more]This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium sec
Distribution and functional significance of the endothelin receptor subtypes in the rat adrenal gland.
Cell Tissue Res. 1997 . The receptors, ETA-R and ETB-R, belong to the superfamily of G protein-coupled receptors. The ETA subtype is selective for ET-1 and ET-2 compared to ET-3, whereas the ETB subtype is unable to distinguish among these three peptides.
Distribution and functional significance of the endothelin receptor subtypes in the rat adrenal gland.
Cell Tissue Res. 1997 . The receptors, ETA-R and ETB-R, belong to the superfamily of G protein-coupled receptors. The ETA subtype is selective for ET-1 and ET-2 compared to ET-3, whereas the ETB subtype is unable to distinguish among these three peptides.