LRP5 - LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5Family:LDLLRP
Synonyms:Low density lipoprotein receptor-related protein 7,LRP7,LR3
External
links:Entrez Gene, Omim
Summary: (from NCBI-Entrez) ..[read more]This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by
A new low density lipoprotein receptor related protein, LRP5, is expressed in hepatocytes and adrenal cortex, and recognizes apolipoprotein E (Kim et al. 1998.
Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling
(Li et al. 2005) . SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor (Semenov et al. 2005).
Receptor FZD1 - FRIZZLED 1 PRECURSORandLigand WNT7B - WINGLESS-TYPE MMTV INTEGRATION SITE FAMILY ...[read more..]
Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5 (Wang et al. 2005).
Receptor FZD10 - FRIZZLED 10 PRECURSORandLigand WNT7B - WINGLESS-TYPE MMTV INTEGRATION SITE FAMILY ...[read more..]
Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5
(Wang et al. 2005).
LRP5 - LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 5
Family:LDLLRP
Receptor LRP5 interacts with:
All interactions in Receptor family ( LDLLRP )
Gene Expression data