Summary: (from NCBI-Entrez)
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The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a c
Receptor TSHR interacts with:
Ligand TSHB - THYROID-STIMULATING HORMONE, BETA CHAIN and Ligand CGA - CHORIONIC GONADOTROPIN, ALPHA CHAIN[read more..] Ligand GPHA2 - GLYCOPROTEIN HORMONE ALPHA 2 and Ligand GPHB5 - GLYCOPROTEIN HORMONE BETA 5[read more..] Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor.
J Clin Invest. 2002 .
Gene Expression data
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OocyteDevelopment
PreEmbryoHuman
PreEmbryoMouse
PreimplantMmEmbryo
Follicle_Maturation_and_Ovulation_POnly
Castrillon_Ovary_Set
Castrillon_Soma_Set
EmbryonicOvary
Mm_Testis_Development
NormEndometrium
PituitaryAdenoma
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Preimplantation Mouse Embryo
Description :
Fields :
Experiment: Testis development
Testes of mice at days 0, 3, 6, 8, 10, 14, 18, 20, 30, 35, and 56 of age.
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{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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Experiment: Pituitary adenoma subtypes
Normal pituitary, pituitary adenomas secreting GH, PRL, or ACTH, and non-functioning adenoma.
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Experiment: Preimplantation mouse embryo
{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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