Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest t
Baynash AG, et al. (Cell, 1994)found that EDN3 interacts with endothelin-B receptor, which is essential in the development of neural crest-derived cell lineages.
Identification of specific regions of the human endothelin-B receptor required for high affinity binding with endothelin-3.
Biochim Biophys Acta. 1994 .
EDNRB - ENDOTHELIN RECEPTOR TYPE B, ISOFORM 1
Family:7TM|A|Polypeptide|Endothelin/CCK/Gastrin releasing peptide
Receptor EDNRB interacts with:
All interactions in Receptor family ( 7TM|A|Polypeptide|Endothelin/CCK/Gastrin releasing peptide )
Gene Expression data