Summary: (from NCBI-Entrez) ..[read more]Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for
Bombesin, neuromedin B and neuromedin C interact with a common rat pancreatic phosphoinositide-coupled receptor, but are differentially regulated by guanine nucleotides (Sekar et al. 1991). Neuromedin-C was approximately 50-fold more potent than neuromedin B in elevating [Ca(2+)](i) in astrocytes and Chinese hamster ovary (CHO) cells expressing human bombesin BB2 receptors (Mason et al. 2002).
Bombesin, neuromedin B and neuromedin C interact with a common rat pancreatic phosphoinositide-coupled receptor, but are differentially regulated by guanine nucleotides (Sekar et al. 1991).Neuromedin-C was approximately 50-fold more potent than neuromedin B in elevating [Ca(2+)](i) in astrocytes and Chinese hamster ovary (CHO) cells expressing human bombesin BB2 receptors (Mason et al. 2002).
GRPR - GASTRIN-RELEASING PEPTIDE RECEPTOR
Family:7TM|A|Polypeptide|Endothelin/CCK/Gastrin releasing peptide
Receptor GRPR interacts with:
All interactions in Receptor family ( 7TM|A|Polypeptide|Endothelin/CCK/Gastrin releasing peptide )
Gene Expression data