Summary: (from NCBI-Entrez) ..[read more]This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized deg
Crystal structure at 1.9 angstroms of the urokinase receptor complexed with the urokinase amino-terminal fragment and an antibody against the receptor reveals that the three domains of urokinase receptor form a concave shape with a central cone-shaped cavity where the urokinase fragment inserts (Huai et al. 2006).