Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are req
Syndecan 2 proteoglycan interacts with the C-terminal heparin-binding domain of fibronectin at the highly sulfated cluster(s), to result in the induction of stress fiber formation in cooperation with integrin alpha-5-beta-1 (Kusano et al. 2000).