Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene i
Syndecan-4, when present in significant amounts, promotes beta-1 integrin-dependent cell spreading and stress fiber formation in response to ADAM12 (Thodeti et al. 2003).