Summary: (from NCBI-Entrez) ..[read more]This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternativ
Identification of a cDNA encoding a long form of prolactin receptor in human hepatoma and breast cancer cells. Molec. Endocr. 3: 1455-1461, 1989. . Upon binding prolactin the long and short isoforms of the PRLR were internalized at different rates, the long-PRLR more rapidly than short-PRLR (57% and 33% respectively internalized at 15 min) (Schuler et al. 2001).
PRLR - PROLACTIN RECEPTOR LONG FORM PRECURSOR, HEPATOMA AND BREAST CANCER CELLS
Family:Cytokine1R|PRLR
All interactions in Receptor family ( Cytokine1R|PRLR )
Gene Expression data