Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhes
Silverstein RL, et al. (J Bio Chem. 1992) transfected the sense and antisense cDNA of CD36 (glycoprotein IV) into melanoma cells and found that CD36 is a thrombospondin receptor.
Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake.
J Biol Chem. 1999 Jan 1;274(1):41-7..