Summary: (from NCBI-Entrez) ..[read more]This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombo
Gao AG, et al. (J Biol Chem. 1996) reported that CD47 is a receptor for the C-terminal domain of thrombospondin. Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.