Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.
Schwann cells bind to collagen type V via syndecan-3-dependent binding to a novel high affinity heparin binding site in the alpha4(V)-NTD (The experiments were done in rats and there is not yet a human ortholog in NCBI Gene database. Thus, the closest human homolog is listed here) (Edman et al. 2002).