NTRK1 - NEUROTROPHIC TYROSINE KINASE, RECEPTOR, TYPE 1
Family: RTK|NGFR/NTR/TRK
Synonyms: TYROSINE KINASE RECEPTOR, TRK|TYROSINE KINASE RECEPTOR A, TRKA
External
links: Entrez Gene ,
Omim
Summary: (from NCBI-Entrez)
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This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to ce
Receptor NTRK1 interacts with:
Ligand NGFB - NERVE GROWTH FACTOR, BETA SUBUNIT[read more..] Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.
Nature. 1999 Ligand NTF5 - NEUROTROPHIN 5[read more..] Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system.
Genes Dev. 2000
Gene Expression data
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OocyteDevelopment
PreEmbryoHuman
PreEmbryoMouse
PreimplantMmEmbryo
Follicle_Maturation_and_Ovulation_POnly
Castrillon_Ovary_Set
Castrillon_Soma_Set
EmbryonicOvary
Mm_Testis_Development
NormEndometrium
PituitaryAdenoma
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Preimplantation Mouse Embryo
Description :
Fields :
Experiment: Testis development
Testes of mice at days 0, 3, 6, 8, 10, 14, 18, 20, 30, 35, and 56 of age.
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Experiment: Pituitary adenoma subtypes
Normal pituitary, pituitary adenomas secreting GH, PRL, or ACTH, and non-functioning adenoma.
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Experiment: Preimplantation mouse embryo
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