The disintegrin domain of ADAM-9 can function as an adhesion molecule by interacting with an alpha-v-beta-5 integrin (Zhou et al 2001).

ICAM-4 is a red cell intercellular adhesion molecule. Cell transfectants expressing various integrins were used to demonstrate that integrins alpha-L-beta-2, alpha-M-beta-2, and alpha-IIb-beta-3 bind specifically and dose dependently to the recombinant ICAM-4-Fc protein. Cell surface ICAM-4 interacts with the cell surface alpha-V-beta-3 integrin (Hermand et al. 2004).

Substrate specificity of alpha(v)beta(3) integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activation. Zheng DQ et al. The alpha(v)beta(3) integrin has been shown to bind several ligands, including osteopontin and vitronectin. Its role in modulating cell migration and downstream signaling pathways in response to specific extracellular matrix ligands has been investigated in this study. ... . We conclude therefore that alpha(v)beta(3) exists in multiple functional states that can bind either selectively vitronectin or both vitronectin and osteopontin and that can differentially activate cell migration and intracellular signaling pathways in a ligand-specific manner.