Summary: (from NCBI-Entrez) ..[read more]This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a tra
Quinn TP,et al. Proc Natl Acad Sci U S A. 1993 reported that Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and Flk-1 binds VEGF with high affinity, undergoes autophosphorylation, and mediates VEGF-dependent Ca2+ efflux in Xenopus oocytes injected with Flk-1 mRNA.