Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity.
Schall TJ, et al. (Cell. 1990) cloned a human tumor necrosis factor (TNF) binding protein, which, transfected into human embryonic kidney cells specifically bind both 125I-labeled and biotinylated TNF-alpha.
In non-neuronal cells, coexpression of human NgR1, p75 and LINGO-1 conferred responsiveness to oligodendrocyte myelin glycoprotein, as measured by RhoA activation (Mi et al. 2004).
TNFRSF1B - TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B
Family:TNFNGF
Receptor TNFRSF1B interacts with:
All interactions in Receptor family ( TNFNGF )
Gene Expression data