Ornitz DM, et al. (J Biol Chem. 1996) carried out a series of experiments and figured out the pairship of fibroblast growth factor family and their receptors.

Ornitz DM, et al. (J Biol Chem. 1996) carried out a series of experiments and figured out the pairship of fibroblast growth factor family and their receptors.

Ornitz DM., et al. (J Biol Chem., 1996)studied the receptor specificity of the fibroblast growth factor family.

Bellosta P., et al. (Mol Cell Biol, 2001) identified the receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis, found FGF4 can bind and activate all FGF receptor members, FGFR1, FGFR2, FGFR3 and FGF4.

Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7). Igarashi M,et al . A newly identified member of the fibroblast growth factor (FGF) family, designated FGF-10, is expressed during development and preferentially in adult lung. The predicted FGF-10 protein is most related to keratinocyte growth factor (KGF, or FGF-7). The latter is unique among FGFs in that it binds and signals only through the FGF receptor (FGFR2b) isoform KGF receptor (KGFR) expressed specifically by epithelial cells.

Receptor specificity of the fibroblast growth factor family. (Ornitz et al. 1996). In the XY gonad at 11.5 dpc, FGFR2 was found in the nuclei of scattered cells in the interior of the gonad. This nuclear localization of FGFR2 was not observed in XX gonads. FGF9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination (Schmahl et al. 2004).

Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization. Blood. 1998

Activation of fibroblast growth factor (FGF) receptors by recombinant human FGF-5. Oncogene. 1993