Summary: (from NCBI-Entrez) ..[read more]This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and
Ornitz DM, et al. (J Biol Chem. 1996) carried out a series of experiments and figured out the pairship of fibroblast growth factor family and their receptors.
Ornitz DM, et al. (J Biol Chem. 1996) carried out a series of experiments and figured out the pairship of fibroblast growth factor family and their receptors.
Bellosta P., et al. (Mol Cell Biol, 2001) identified the receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis, found FGF4 can bind and activate all FGF receptor members, FGFR1, FGFR2, FGFR3 and FGF4.
Bellosta P., et al. (Mol Cell Biol, 2001) identified the receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis, found FGF8 can bind and activate FGFR3 and FGF4.
Receptor FGFR3 interacts with:
All interactions in Receptor family ( RTK|FGR )
Gene Expression data