Summary: (from NCBI-Entrez) ..[read more]This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternative
PTN signals through ligand-dependent receptor inactivation of RPTP beta/zeta to increase levels of tyrosine phosphorylation of beta-catenin to initiate downstream signaling. PTN is the first natural ligand identified for any of the RPTP family (Meng et al. 2000).
PTPRZ1 - PROTEIN-TYROSINE PHOSPHATASE ZETA PRECURSOR
Family:RPTP|RPTPZETA
Receptor PTPRZ1 interacts with:
All interactions in Receptor family ( RPTP|RPTPZETA )
Gene Expression data