TGFBR1 - TGF-BETA RECEPTOR TYPE I PRECURSORFamily:SerThrK|ALK
Synonyms:(TGR1_HUMAN) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5)
External
links:Entrez Gene, Omim
Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutation
Receptor TGFBR1 interacts with:
Receptor TGFBR2 - TGF-BETA RECEPTOR TYPE II PRECURSORandLigand TGFB1 - TRANSFORMING GROWTH FACTOR, BETA-1[read more..]
A complex of TGF-beta1/ALK5/TGF receptor type II is involved for TGF-beta signaling. Cell. 2003 .