Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and th
The integrin alpha(7)beta(1) is the major laminin-binding integrin in skeletal, heart, and smooth muscle and is a receptor for laminin-1 and -2 Meilenz et al. 2001 .
The integrin alpha(7)beta(1) is the major laminin-binding integrin in skeletal, heart, and smooth muscle and is a receptor for laminin-1 and -2 (Meilenz et al. 2001).
Form and function: the laminin family of heterotrimers. Laminin-1 is composed of the three subunits alpha-1, beta-1 and gamma-1 (Colognato & Yurchenco 2000).
Form and function: the laminin family of heterotrimers. Laminin-2 is composed of the three subunits alpha-2, beta-1 and gamma-1 (Colognato & Yurchenco 2000).