Summary: (from NCBI-Entrez) ..[read more]This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain,
Plasmin specifically interacts with alpha(9)beta(1).Its effect on cell migration was dependent on an interaction of the kringle domains of plasmin with alpha(9)beta(1) as well as the catalytic activity of plasmin (Majumdar et al. 2004).
Receptor ITGB1 - INTEGRIN BETA-1 PRECURSORandLigand ADAM12 - A DISINTEGRIN AND METALLOPROTEINASE DOMAI ...[read more..]
Eto et al. (2000) show that integrin alpha-9-beta-1 specifically interacts with the recombinant ADAMs-12 disintegrin domain in an RGD-independent manner. The interaction between ADAM-12 and alpha-9-beta-1 supports cell-cell interaction.
Receptor ITGB1 - INTEGRIN BETA-1 PRECURSORandLigand ADAM15 - A DISINTEGRIN AND METALLOPROTEINASE DOMAI ...[read more..]
Eto et al. (2000) show that integrin alpha-9-beta-1 specifically interacts with the recombinant ADAMs-15 disintegrin domain in an RGD-independent manner. The interaction between ADAM-15 and alpha-9-beta-1 supports cell-cell interaction.