Summary: (from NCBI-Entrez) ..[read more]This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that i
Slusarski DC, et al. (Nature, 1997) show that the rat protein Frizzled-2 causes an increase in the release of intracellular calcium which is enhanced by Xwnt-5a, a member of the Wnt family and suggested that Wnt can signal through Frizzled 2.