SMO - SMOOTHENED HOMOLOG PRECURSOR
Family: 7TM|Frizzled_Smo
Synonyms: Smoothened homolog precursor (SMO) (Gx protein) (SMOH).
External
links: Entrez Gene ,
Omim
Summary: (from NCBI-Entrez)
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The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein comp
Receptor SMO interacts with:
Receptor PTCH - PATCHED PROTEIN HOMOLOG 1 and Ligand SHH - SONIC HEDGEHOG HOMOLOG[read more..] Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells.
J Biol Chem. 2006
Gene Expression data
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OocyteDevelopment
PreEmbryoHuman
PreEmbryoMouse
PreimplantMmEmbryo
Follicle_Maturation_and_Ovulation_POnly
Castrillon_Ovary_Set
Castrillon_Soma_Set
EmbryonicOvary
Mm_Testis_Development
NormEndometrium
PituitaryAdenoma
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Preimplantation Mouse Embryo
Description :
Fields :
Experiment: Testis development
Testes of mice at days 0, 3, 6, 8, 10, 14, 18, 20, 30, 35, and 56 of age.
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{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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Experiment: Pituitary adenoma subtypes
Normal pituitary, pituitary adenomas secreting GH, PRL, or ACTH, and non-functioning adenoma.
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{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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Experiment: Preimplantation mouse embryo
{%="("+prot_type.slice(0,3)+") "+GeneSymbol%>
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