Summary: (from NCBI-Entrez) ..[read more]This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays
Shimizu K, et al. (Biochem Biophys Res Commun. 2000) studied the physical interaction between the three DSL proteins and respective Notch receptors and their results suggest that Delta1, Jagged1, and Jagged2 are ligands for Notch1 and Notch3 receptors.
Receptor NOTCH3 interacts with:
All interactions in Receptor family ( Notch )
Gene Expression data