Summary: (from NCBI-Entrez) ..[read more]The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are i
RANK, the receptor activator of NF-kappaB, and its ligand RANKL (initially termed TRANCE, also termed ODF and OPGL), are a TNF superfamily receptor-ligand pair that govern the development and function of osteoclasts, lymphoid tissue, and mammary epithelium (lam et al. 2001). Crystal structure of RANK ligand involved in bone metabolism.
(Ito & Hata 2004).
TNFRSF11A - TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A PRECURSOR
Family:TNFNGF|TNR8
Receptor TNFRSF11A interacts with:
All interactions in Receptor family ( TNFNGF|TNR8 )
Gene Expression data