ul_10----
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PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name KRT18( Description: keratin 18. )
Synonyms CK-18; CYK18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; K18; Keratin-18
GO annotations GO_component: intermediate filament [PMID 2434380]
GO_function:protein binding [PMID 15731013]; structural constituent of cytoskeleton
GO_process: morphogenesis [PMID 2434380]
RefSeq accession NP_000215
SwissProt accession P05783
GO Pathway:
GO:0006605     protein targeting
Sequence:(RefSeq accession:NP_000215; substrate region highlighted if known)
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MSFTTRSTFS TNYRSLGSVQ APSYGARPVS SAASVYAGAG GSGSRISVSR STSFRGGMGS
GGLATGIAGG LAGMGGIQNE KETMQSLNDR LASYLDRVRS LETENRRLES KIREHLEKKG
PQVRDWSHYF KIIEDLRAQI FANTVDNARI VLQIDNARLA ADDFRVKYET ELAMRQSVEN
DIHGLRKVID DTNITRLQLE TEIEALKEEL LFMKKNHEEE VKGLQAQIAS SGLTVEVDAP
KSQDLAKIMA DIRAQYDELA RKNREELDKY WSQQIEESTT VVTTQSAEVG AAETTLTELR
RTVQSLEIDL DSMRNLKASL ENSLREVEAR YALQMEQLNG ILLHLESELA QTRAEGQRQA
QEYEALLNIK VKLEAEIATY RRLLEDGEDF NLGDALDSSN SMQTIQKTTT RRIVDGKVVS
ETNDTKVLRH
Records:
Category Evidence Reference
A Mutagenesis Ku NO, Liao J, Omary MB., Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins., [9524113]
End of Record Details