ul_10035----<table width="100%" border="0" cellpadding="5" cellspacing="1" bgcolor="#666666" >
    <tr>
    <td colspan="2" bgcolor="#999999"><table width="100%" border="0" cellspacing="0">
        <tr>
          <td width="91%" align="left"><strong>Record details:</strong> </td>
          <td width="9%" align="right"><a href="javascript:hide('ul_10035')" class="small">Hide</a></td>
       </tr>
      </table></td>
  </tr>
    <tr bgcolor="#CCCCCC">
    <td colspan="2"><strong>PPBD protein </strong></td>
    
  </tr>
 <tr>
    <td bgcolor="#FFFFFF" colspan="2"><table width="100%" border="0" cellpadding="5" cellspacing="1">
      <tr>
        <td width="25%">Gene name </td>
        <td><a href="ppbd.php?s=GRB2" title="PPBD proteins are named by using their Entrez Gene Name.">GRB2</a></td>
      </tr> 
      	<tr>
        <td>Synonyms </td>
        <td>GRB2</td>
      </tr>
       <tr>
        <td>GO annotations </td>
        <td>GO_component: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005829>cytosol</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=14722116>14722116</a>]<br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005154>epidermal growth factor receptor binding</a>
                     [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=12577067>12577067</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0043560>insulin receptor substrate binding</a> [PMID
                     <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=8388384>8388384</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005070>SH3/SH2 adaptor activity</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=8253073>8253073</a>]<br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007267>cell-cell signaling</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=8253073>8253073</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007173>epidermal</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007173>growth factor receptor signaling pathway</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=1322798>1322798</a>];
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0008286>insulin receptor signaling pathway</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=8388384>8388384</a>];
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007242>intracellular signaling cascade</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007265>Ras protein signal</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007265>transduction</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=8253073>8253073</a>]</td>
      </tr>
      <tr>	
      <tr>
        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_987102" target="_blank" >NP_987102</a></td>
      </tr>
      <tr>
        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/" target="_blank" ></a></td>
      </tr>
    </table></td></tr>
    
    <tr bgcolor="#CCCCCC">
    
    <td  colspan="2"><strong>Substrate protein </strong></td>
  </tr>
  <tr>
    <td bgcolor="#FFFFFF" colspan="2"><table width="100%" border="0" cellpadding="5" cellspacing="1">
      <tr>
        <td width="25%">Gene name </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=full_report&list_uids=7048
" target="_blank"  title="Substrate proteins are named by using their Entrez Gene Name.">TGFBR2</a></td>
      </tr>
      	<tr>
        <td>Synonyms </td>
        <td>TBETAR-II</td>
      </tr><tr>
        <td>GO annotations </td>
        <td>GO_component: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016021>integral to membrane</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016020>membrane</a><br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005524>ATP binding</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0000287>magnesium ion binding</a>;
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0030145>manganese ion binding</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0000166>nucleotide binding</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005515>protein binding</a>
                     [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=8242742>8242742</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004872>receptor activity</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016740>transferase activity</a>;
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005026>transforming growth factor beta receptor activity, type II</a>
                     [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=7761852>7761852</a>]<br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0008284>positive regulation of cell proliferation</a>
                     [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=7761852>7761852</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006470>protein amino acid dephosphorylation</a>;
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006468>protein amino acid phosphorylation</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007178>transmembrane receptor</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007178>protein serine/threonine kinase signaling pathway</a></td>
      </tr>
      <tr>		
      	<tr>
        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001020018" target="_blank" >NP_001020018</a></td>
      </tr>
      <tr>
        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/" target="_blank" ></a></td>
      </tr>
    </table></td>
  </tr><tr>
    <td colspan="2" bgcolor="#CCCCCC"><strong>Sequence:</strong>(RefSeq accession:<a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001020018" target="_blank" >NP_001020018</a>; substrate region highlighted 
if known)</td></tr><tr bgcolor="#FFFFFF"><td colspan="2"><table align="center"><tr><td class="sequence" align="right">1<br>61<br>121<br>181<br>241<br>301<br>361<br>421<br>481<br>541<br></td><td><span class="sequence">MGRGLLRGLW PLHIVLWTRI ASTIPPHVQK SDVEMEAQKD EIICPSCNRT AHPLRHINND <br>MIVTDNNGAV KFPQLCKFCD VRFSTCDNQK SCMSNCSITS ICEKPQEVCV AVWRKNDENI <br>TLETVCHDPK LPYHDFILED AASPKCIMKE KKKPGETFFM CSCSSDECND NIIFSEEYNT <br>SNPDLLLVIF QVTGISLLPP LGVAISVIII FYCYRVNRQQ KLSSTWETGK TRKLMEFSEH <br>CAIILEDDRS DISSTCANNI NHNTELLPIE LDTLV<font color='red'>GKGRF AEVYKAKLKQ NT</font>SEQFETVA <br>VKIFPYEEYA SWKTEKDIFS DINLKHENIL QFLTAEERKT ELGKQYWLIT AFHAKGNLQE <br>YLTRHVISWE DLRKLGSSLA RGIAHLHSDH TPCGRPKMPI VHRDLKSSNI LVKNDLTCCL <br>CDFGLSLRLD PTLSVDDLAN SGQVGTARYM APEVLESRMN LENVESFKQT DVYSMALVLW <br>EMTSRCNAVG EVKDYEPPFG SKVREHPCVE SMKDNVLRDR GRPEIPSFWL NHQGIQMVCE <br>TLTECWDHDP EARLTAQCVA ERFSELEHLD RLSGRSCSEE KIPEDGSLNT TK</span></td></tr></table></td></tr><tr>
    <td colspan="2" bgcolor="#CCCCCC"><strong>Records:</strong></td>
  </tr><tr>
    <td colspan="2" bgcolor="#FFFFFF">
       <table width="90%" align="center" border="0" cellpadding="5" cellspacing="1" bgcolor="#DDDDDD">
          <tr bgcolor="#EFEFEF">
                <td align="center"><b>Category</b></td>
                <td align="center"><b>Evidence</b></td>
                <td align="center"><b>Reference</b></td>
           </tr><tr bgcolor="#FFFFFF">
                <td  align="center">A</td>
                <td  align="center">Mutagenesis</td>
                <td  align="left"><a>, , [<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17440088" target="_blank" >17440088</a>] </a></td>
            </tr></table></td>
  </tr> <tr>
    <td colspan="2" bgcolor="#999999" align="right"><strong>End of Record Details</strong></td>
  </tr></table>