ul_10054----
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PPBD protein
Gene name Hck
Synonyms Hck
GO annotations GO_component: membrane
GO_function:ATP binding; nucleotide binding; protein binding [PMID 7859737] [PMID 12029088]; protein-tyrosine kinase activity [PMID 3496523]; transferase activity
GO_process: intracellular signaling cascade; mesoderm development [PMID 3453117]; protein amino acid phosphorylation [PMID 3496523]
RefSeq accession NP_002101
SwissProt accession
Substrate protein
Gene name Flt3
Synonyms Flt3
GO annotations GO_component: integral to plasma membrane [PMID 8394751]; membrane
GO_function:ATP binding; nucleotide binding; receptor activity; transferase activity; vascular endothelial growth factor receptor activity [PMID 8394751]
GO_process: positive regulation of cell proliferation [PMID 7507245]; protein amino acid phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway [PMID 7507245]
RefSeq accession NP_004110
SwissProt accession
Sequence:(RefSeq accession:NP_004110; substrate region highlighted if known)
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MPALARDAGT VPLLVVFSAM IFGTITNQDL PVIKCVLINH KNNDSSVGKS SSYPMVSESP
EDLGCALRPQ SSGTVYEAAA VEVDVSASIT LQVLVDAPGN ISCLWVFKHS SLNCQPHFDL
QNRGVVSMVI LKMTETQAGE YLLFIQSEAT NYTILFTVSI RNTLLYTLRR PYFRKMENQD
ALVCISESVP EPIVEWVLCD SQGESCKEES PAVVKKEEKV LHELFGTDIR CCARNELGRE
CTRLFTIDLN QTPQTTLPQL FLKVGEPLWI RCKAVHVNHG FGLTWELENK ALEEGNYFEM
STYSTNRTMI RILFAFVSSV ARNDTGYYTC SSSKHPSQSA LVTIVGKGFI NATNSSEDYE
IDQYEEFCFS VRFKAYPQIR CTWTFSRKSF PCEQKGLDNG YSISKFCNHK HQPGEYIFHA
ENDDAQFTKM FTLNIRRKPQ VLAEASASQA SCFSDGYPLP SWTWKKCSDK SPNCTEEITE
GVWNRKANRK VFGQWVSSST LNMSEAIKGF LVKCCAYNSL GTSCETILLN SPGPFPFIQD
NISFYATIGV CLLFIVVLTL LICHKYKKQF RYESQLQMVQ VTGSSDNEYF YVDFREYEYD
LKWEFPRENL EFGKVLGSGA FGKVMNATAY GISKTGVSIQ VAVKMLKEKA DSSEREALMS
ELKMMTQLGS HENIVNLLGA CTLSGPIYLI FEYCCYGDLL NYLRSKREKF HRTWTEIFKE
HNFSFYPTFQ SHPNSSMPGS REVQIHPDSD QISGLHGNSF HSEDEIEYEN QKRLEEEEDL
NVLTFEDLLC FAYQVAKGME FLEFKSCVHR DLAARNVLVT HGKVVKICDF GLARDIMSDS
NYVVRGNARL PVKWMAPESL FEGIYTIKSD VWSYGILLWE IFSLGVNPYP GIPVDANFYK
LIQNGFKMDQ PFYATEEIYI IMQSCWAFDS RKRPSFPNLT SFLGCQLADA EEAMYQNVDG
RVSECPHTYQ NRRPFSREMD LGLLSPQAQV EDS
Records:
Category Evidence Reference
A Mutagenesis , , [17668209]
End of Record Details