ul_10071----
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PPBD protein
Gene name src
Synonyms src
GO annotations GO_component: integral to membrane; membrane
GO_function:ATP binding; nucleotide binding; protein binding [PMID 8681387] [PMID 9763511]; protein-tyrosine kinase activity [PMID 9020193]; SH2 domain binding [PMID 8070403]; SH3/SH2 adaptor activity [PMID 9020193]; transferase activity
GO_process: protein amino acid phosphorylation; protein kinase cascade [PMID 9020193]; signal complex formation [PMID 9924018]
RefSeq accession NP_938033
SwissProt accession
Substrate protein
Gene name PDK1
Synonyms PDK1
GO annotations GO_component: cytoplasm [PMID 9637919]; plasma membrane [PMID 9637919]
GO_function:3-phosphoinositide-dependent protein kinase activity [PMID 9368760]; ATP binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transferase activity
GO_process: actin cytoskeleton organization and biogenesis [PMID 10792047]; insulin receptor signaling pathway [PMID 10792047]; protein amino acid phosphorylation [PMID 9368760]
RefSeq accession NP_002604
SwissProt accession
Sequence:(RefSeq accession:NP_002604; substrate region highlighted if known)
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MARTTSQLYD AVPIQSSVVL CSCPSPSMVR TQTESSTPPG IPGGSRQGPA MDGTAAEPRP
GAGSLQHAQP PPQPRKKRPE DFKFGKILGE GSFSTVVLAR ELATSREYAI KILEKRHIIK
ENKVPYVTRE RDVMSRLDHP FFVKLYFTFQ DDEKLYFGLS YAKNGELLKY IRKIGSFDET
CTRFYTAEIV SALEYLHGKG IIHRDLKPEN ILLNEDMHIQ ITDFGTAKVL SPESKQARAN
SFVGTAQYVS PELLTEKSAC KSSDLWALGC IIYQLVAGLP PFRAGNEYLI FQKIIKLEYD
FPEKFFPKAR DLVEKLLVLD ATKRLGCEEM EGYGPLKAHP FFESVTWENL HQQTPPKLTA
YLPAMSEDDE DCYGNYDNLL SQFGCMQVSS SSSSHSLSAS DTGLPQRSGS NIEQYIHDLD
SNSFELDLQF SEDEKRLLLE KQAGGNPWHQ FVENNLILKM GPVDKRKGLF ARRRQLLLTE
GPHLYYVDPV NKVLKGEIPW SQELRPEAKN FKTFFVHTPN RTYYLMDPSG NAHKWCRKIQ
EVWRQRYQSH PDAAVQ
Records:
Category Evidence Reference
A Mutagenesis , , [18024423]
End of Record Details