ul_1099----
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PPBD protein
Gene name YWHAZ
Synonyms KCIP-1; Protein kinase C inhibitor protein 1
GO annotations GO_component:
GO_function:protein domain specific binding; transcription factor binding [PMID 16114898]
GO_process:
RefSeq accession NP_003397
SwissProt accession P63104
Substrate protein
Gene name Hap1( Description: huntingtin-associated protein 1. )
Synonyms
GO annotations GO_component: actin cytoskeleton; cytoplasmic membrane-bound vesicle; early endosome; late endosome
GO_function:protein binding
GO_process: development; early endosome to late endosome transport; nervous system development; synaptic transmission; vesicle transport along microtubule
RefSeq accession NP_077047
SwissProt accession P54256
GO Pathway:
GO:0007399     nervous system development
Sequence:(RefSeq accession:NP_077047; substrate region highlighted if known)
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MRPKDQVQSS AGDGTGSGDP ATGTPTTQPA ADPAPEPSAE PKPAPAQGTG SGQKSGSRTK
TGGSFCRSRI RGDSDAPWTR YIFQGPYGPR ATGLGTGRAE GIWKTPAAYI GRRPGVSGPE
RAAFIRELQE ALCPNPLPRK KITEDDIKVM LYLLEEKERD LNTAARIGQS LVKQNSVLME
ENNKLETMLG SAREEILHLR KQVNLRDDLL QLYSDSDDDE EDEEDEEEEE GEEEEREGQR
DQDQQHDHPY GAPKPPPKAE TLHHCPQLEA LKQKLKLLEE ENDHLREEAS HLDNLEDKEQ
MLILECVEQF SEASQQMAEL SEVLVLRLEG YERQQKEITQ LQAEITKLQQ RCQSYGAQTE
KLQQQLASEK GVHPESLRAG SHMQDYGSRP RERQEDGKSH RQRSSMPAGS VTHYGYSVPL
DALPSFPETL AEELRTSLRK FITDPAYFME RCDTRCREER KKEQGTMPPP PVQDLKPPED
FEAPEELVPE EELGAIEEVG TAEDGPAEET EQASEETEAW EEVEPEVDEA TRMNVVVSAL
EASGLGPSHL DMKYVLQQLS NWQDAHSKRQ QKQKVVPKGE CSRRGHPPAS GTSYRSSTL
Records:
Category Evidence Reference
A Mutagenesis Rong J, Li S, Sheng G, Wu M, Coblitz B, Li M, Fu H, Li XJ., 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking., [17166838]
End of Record Details