ul_128----
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PPBD protein
Gene name YWHAB( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide. )
Synonyms GW128; HS1; KCIP-1; Protein 1054; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm [PMID 12963375]; perinuclear region [PMID 12963375]
GO_function:monooxygenase activity; protein domain specific binding
GO_process:
RefSeq accession NP_003395
SwissProt accession P31946
Substrate protein
Gene name Prkcz( Description: protein kinase C, zeta. )
Synonyms 14-3-3-zetaisoform; EC 2.7.11.13; Pkcz; nPKC-zeta; r14-3-3
GO annotations GO_component: apical cortex; cell cortex; cytoplasm; membrane fraction; plasma membrane; tight junction
GO_function:atypical protein kinase C activity; diacylglycerol binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein-tyrosine kinase activity; transferase activity
GO_process: anti-apoptosis; intracellular signaling cascade; microtubule cytoskeleton organization and biogenesis; protein amino acid phosphorylation; signal transduction
RefSeq accession NP_071952
SwissProt accession P09217
Sequence:(RefSeq accession:NP_071952; substrate region highlighted if known)
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MPSRTDPKMD RSGGRVRLKA HYGGDILITS VDPTTTFQDL CEEVRDMCGL HQQHPLTLKW
VDSEGDPCTV SSQMELEEAF RLACQGRDEV LIIHVFPSIP EQPGMPCPGE DKSIYRRGAR
RWRKLYRANG HLFQAKRFNR RAYCGQCSER IWGLARQGYR CINCKLLVHK RCHVLVPLTC
RRHMDSVMPS QEPPVDDKND GVDLPSEETD GIAYISSSRK HDNIKDDSED LKPVIDGVDG
IKISQGLGLQ DFDLIRVIGR GSYAKVLLVR LKKNDQIYAM KVVKKELVHD DEDIDWVQTE
KHVFEQASSN PFLVGLHSCF QTTSRLFLVI EYVNGGDLMF HMQRQRKLPE EHARFYAAEI
CIALNFLHER GIIYRDLKLD NVLLDADGHI KLTDYGMCKE GLGPGDTTST FCGTPNYIAP
EILRGEEYGF SVDWWALGVL MFEMMAGRSP FDIITDNPDM NTEDYLFQVI LEKPIRIPRF
LSVKASHVLK GFLNKDPKER LGCRPQTGFS DIKSHAFFRS IDWDLLEKKQ TLPPFQPQIT
DDYGLDNFDT QFTSEPVQLT PDDEDVIKRI DQSEFEGFEY INPLLLSAEE SV
Records:
Category Evidence Reference
A Inference Van Der Hoeven PC, Van Der Wal JC, Ruurs P, Van Blitterswijk WJ., Protein kinase C activation by acidic proteins including 14-3-3., [10769183]
End of Record Details