ul_1381----

Record details:

PPBD protein

Gene name	MKI67( Description: antigen identified by monoclonal antibody Ki-67. )
Synonyms	KIA; Ki-67
GO annotations	GO_component: nucleolus; nucleus GO_function:ATP binding; nucleotide binding; protein binding [PMID 11342549] GO_process: cell cycle; cell proliferation [PMID 8227122]; regulation of progression through cell cycle [PMID 8227122]
RefSeq accession	NP_002408
SwissProt accession	P46013

Substrate protein

Gene name	MKI67IP( Description: MKI67 (FHA domain) interacting nucleolar phosphoprotein. )
Synonyms	NIFK; Nopp34; Nucleolar phosphoprotein Nopp34; Nucleolar protein interacting with the FHA domain of pKI-67; hNIFK
GO annotations	GO_component: condensed nuclear chromosome [PMID 11342549]; cytoplasm [PMID 11342549]; nucleolus [PMID 11342549]; nucleoplasm [PMID 11342549]; nucleus GO_function:nucleotide binding; protein binding [PMID 11342549]; RNA binding [PMID 11342549] GO_process: protein complex assembly [PMID 11342549]; rRNA metabolism [PMID 11342549]; rRNA transcription [PMID 11342549]
RefSeq accession	NP_115766
SwissProt accession	Q9BYG3

Sequence:(RefSeq accession:NP_115766; substrate region highlighted if known)

1
61
121
181
241

MATFSGPAGP ILSLNPQEDV EFQKEVAQVR KRITQRKKQE QLTPGVVYVR HLPNLLDETQ
IFSYFSQFGT VTRFRLSRSK RTGNSKGYAF VEFESEDVAK IVAETMNNYL FGERLLECHF
MPPEKVHKEL FKDWNIPFKQ PSYQSVKRYN RNRTLTQKLR MEERFKKKER LLRKKLAKKG
IDYDFPSLIL QKTESISKTN RQTSTKGQVL RKKKKKVSGT LDTPEKTVDS QGPTPVCTPT
FLERRKSQVA ELNDDDKDDE IVFKQPISCV KEEIQETQTP THSRKKRRRS SNQ

Records:

Category	Evidence	Reference
A	Mutagenesis	Takagi M, Sueishi M, Saiwaki T, Kametaka A, Yoneda Y., A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis., [11342549]

End of Record Details