ul_157----
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PPBD protein
Gene name YWHAB( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide. )
Synonyms GW128; HS1; KCIP-1; Protein 1054; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm [PMID 12963375]; perinuclear region [PMID 12963375]
GO_function:monooxygenase activity; protein domain specific binding
GO_process:
RefSeq accession NP_003395
SwissProt accession P31946
Substrate protein
Gene name Tesk1( Description: testis specific protein kinase 1. )
Synonyms EC 2.7.12.1; Testicular protein kinase 1
GO annotations GO_component:
GO_function:magnesium ion binding; manganese ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity
GO_process: spermatogenesis
RefSeq accession NP_113766
SwissProt accession Q63572
GO Pathway:
GO:0006605     protein targeting
Sequence:(RefSeq accession:NP_113766; substrate region highlighted if known)
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MAGERPPLRG PGPGETPVEG PGGAGGGPGR GRPSSYRALR SAVSSLARVD DFDCAEKIGA
GFFSEVYKVR HRQSGQVMVL KMNKLPSNRS NTLREVQLMN RLRHPNILRF MGVCVHQGQL
HALTEYMNGG TLEQLLSSPE PLSWPVRLHL ALDIAQGLRY LHAKGVFHRD LTSKNCLVRR
EDGGFTAVVG DFGLAEKIPV YREGARKEPL AVVGSPYWMA PEVLRGELYD EKADVFAFGI
VLCELIARVP ADPDYLPRTE DFGLDVPAFR TLVGNDCPLP FLLLAIHCCS MEPSARAPFT
EITQHLEQIL EQLPEPTPLA KMPLAKAPLT YNQGSVPRGG PSATLPRSDP RLSRSRSDLF
LPPSPESPPS WGDNLTRVNP FSLREDLRGG KIKLLDTPCK PATPLPLVPP SPLTSTQLPL
VASPESLVQP ETPVRRCRSL PSSPELPRRM ETALPGPGPS PVGPSTEERM DCEGSSPEPE
PPGPAPQLPL AVATDNFIST CSSASQPWSA RPGPSLNNNP PAVVVNSPQG WAREPWNRAQ
HSLPRAAALE RTEPSPPPSA PREQEEGLPC PGCCLSPFSF GFLSMCPRPT PAVARYRNLN
CEAGSLLCHR GHHAKPPTPS LQLPGARS
Records:
Category Evidence Reference
A Mutagenesis Toshima JY, Toshima J, Watanabe T, Mizuno K., Binding of 14-3-3beta regulates the kinase activity and subcellular localization of testicular protein kinase 1., [11555644]
End of Record Details