ul_1610----
Record details: Hide
PPBD protein
Gene name PLK1( Description: polo-like kinase 1 (Drosophila). )
Synonyms EC 2.7.11.21; PLK; PLK-1; Polo-like kinase 1; STPK13; Serine/threonine-protein kinase 13
GO annotations GO_component: centrosome [PMID 11256614]; nucleus
GO_function:ATP binding; nucleotide binding; protein binding [PMID 15070733] [PMID 15654075] [PMID 16439210]; protein serine/threonine kinase activity [PMID 8127874]; transferase activity
GO_process: cell proliferation [PMID 8127874]; mitosis [PMID 9177283]; protein amino acid phosphorylation; regulation of progression through cell cycle [PMID 8127874]
RefSeq accession NP_005021
SwissProt accession P53350
Substrate protein
Gene name MLF1IP( Description: MLF1 interacting protein. )
Synonyms CENP-50; CENP-U; CENP-U(50); CENPU; FLJ23468; Interphase centromere complex protein 24; KLIP1; KSHV latent nuclear antigen-interacting protein 1; MLF1-interacting protein
GO annotations GO_component: chromosome; chromosome, pericentric region; nucleus
GO_function:
GO_process: regulation of transcription, DNA-dependent; transcription
RefSeq accession NP_078905
SwissProt accession Q71F23
GO Pathway:
GO:0005694     chromosome
Sequence:(RefSeq accession:NP_078905; substrate region highlighted if known)
1
61
121
181
241
301
361
MAPRGRRRPR PHRSEGARRS KNTLERTHSM KDKAGQKCKP IDVFDFPDNS DVSSIGRLGE
NEKDEETYET FDPPLHSTAI YADEEEFSKH CGLSLSSTPP GKEAKRSSDT SGNEASEIES
VKISAKKPGR KLRPISDDSE SIEESDTRRK VKSAEKISTQ RHEVIRTTAS SELSEKPAES
VTSKKTGPLS AQPSVEKENL AIESQSKTQK KGKISHDKRK KSRSKAIGSD TSDIVHIWCP
EGMKTSDIKE LNIVLPEFEK THLEHQQRIE SKVCKAAIAT FYVNVKEQFI KMLKESQMLT
NLKRKNAKMI SDIEKKRQRM IEVQDELLRL EPQLKQLQTK YDELKERKSS LRNAAYFLSN
LKQLYQDYSD VQAQEPNVKE TYDSSSLPAL LFKARTLLGA ESHLRNINHQ LEKLLDQG
Records:
Category Evidence Reference
A Peptide library Kang YH, Park JE, Yu LR, Soung NK, Yun SM, Bang JK, Seong YS, Yu H, Garfield S, Veenstra TD, Lee KS., Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1., [17081991]
End of Record Details